TEL. 0824-74-1000
〒727-0023 広島県庄原市七塚町5562
生命科学コースでは、動物、植物、微生物など多様な生物種を用いた様々な研究(卒業論文や修士?博士論文研究等)に学生?教員が日々取り組んでいます(各教員の専門分野についてはこちら)。これまでも大学ホームページなどで研究成果や発表論文を紹介してきましたが、以下、2020年以降の生命科学コース所属研究室の主要な論文や総説、受賞などの業績をまとめてみました。
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<研究論文等> 2025.2.10更新
2025年
Nakanishi T, Tonai S, Ichikawa H, Mori S, Ishihara S, Chang Y, Yamashita Y (2025) Curcumin Suppresses ROS Production and Increases Mitochondrial Activity in Cumulus Cells and Oocytes of COCs Derived From Non-Vascularized Follicles in Pigs. Anim Sci J. 96(1):e70032. doi: 10.1111/asj.70032. 解説
Saitoh Y, Takeda K, Okawachi K, Tanimura
Y (2025) High dose of ascorbic acid induces selective cell growth inhibition and
cell death in human gastric signet-ring cell carcinoma-derived NUGC-4 cells.
Biochim Biophys Acta Gen Subj. 1869(2):130738 解説
齋藤 靖和 複製老化細胞とストレス老化細胞は同質なのか? 月刊 細胞 2025年2月号 36-38. 解説
2024年
Fukunaga K,
Abe A, Ito K, Oikawa K, Tsuji M, Kawase M (2024) Latitudinal adaptation and dispersal pathway suggested by geographical
distribution of transposable elements inserted in the SiPRR37 gene in foxtail millet. Genes and Genetic Systems 99:Article ID 24-00023 解説
菅裕、阿形清和 他 単細胞ホロゾア?多細胞体制の起源 月刊 細胞 2024年5月号 解説
Aoshima H, Mizuno R, Iwatsu Y,
Onishi S, Hyodo S, Ibuki R, Kawagishi H, Saitoh Y (2024) Inhibitory effect of 2-Aza-8-oxohypoxanthine on tyrosinase activity and
melanin production. Cosmetics 11(2): 43. 解説
Okamoto A, Nakanishi T, Tonai S, Shimada M, Yamashita Y (2024) Neurotensin induces sustainable activation of the ErbB-ERK1/2 pathway, which is required for developmental competence of oocytes in mice. Reprod Med Biol. 23(1):e12571 解説
Fukunaga K and Kawase M (2024) Crop Evolution of Foxtail Millet. Plants 13:218. https://doi.org/10.3390/plants130202 解説
2023年
Kondo Y, Ogawa T, Kanno E, Hirono M, Kato-Minoura T, Kamiya R,
Yagi T (2023) IC2 participates in the cooperative activation of outer arm dynein densely
attached to microtubules. Cell Struct Funct. 48(2):175-185. 解説
Tonai S, Nakanishi T, Yamaoka M, Okamoto
A, Shimada M, Yamashita Y (2023) Pre-culture with transferrin-Fe3+ before in vitro maturation improves the developmental competence of porcine oocytes matured in vitro. Reprod Med Biol. 22(1):e12529 解説
福永健二 (2023) アワの遺伝学 雑穀研究 38, 10-17 解説
Yagi T, Toda A, Ichikawa M, Kurisu G (2023) Regulation of motor activity of ciliary outer-arm dynein by the light chain
1; Implications from the structure of the light chain bound to the microtubule-binding
domain of the heavy chain. Biophysics and Physicobiology 解説
齋藤靖和 (2023) 細胞老化に伴う特徴的な変化からみるSenolysis/Senostaticsの可能性 月刊 細胞 Vol. 55(2), 32-35 解説
Yamamoto N, Takeuchi H, Yamaoka M, Nakanishi T, Tonai S,
Nishimura R, Morita T, Nagano M, Kameda S, Genda K, Kawase J, Yamashita Y (2023) Lipopolysaccharide (LPS) suppresses follicle development
marker expression and enhances cytokine expressions, which results in fail to
granulosa cell proliferation in developing follicle in cows.Reprod Biol. 23(1): 100710 解説
2022年
Suzuki H, Watanabe H, Abe Y (2022) Assisted
reproductive techniques for canines: preservation of genetic material in
domestic dogs. Journal of reproduction and development 68: 1-11
Saitoh Y, Yonekura N, Matsuoka D, Matsumoto A (2022) Molecular
hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced
increases in interleukin-1 alpha and interleukin-6 secretion in human gingival
cells. Molecular and Cellular Biochemistry 477:
99-104 解説
Fukunaga K, Abe A, Mukainari Y, Komori K, Tanaka K, Fujihara A, Yaegashi H, Kobayashi M, Ito K, Ohsako T & Kawase M (2022) Recombinant inbred
lines and next-generation sequencing enable rapid identification of candidate
genes involved in morphological and agronomic traits in foxtail millet. Scientific
Reports 解説 プレスリリース
2021年
Saitoh
Y, Yamaguchi Y, Okada Y (2021) Protective effects of dissolved molecular hydrogen against hydrogen peroxide-,
hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. Molecular and Cellular Biochemistry. 476:3613-3622 解説
Seino H,
Kawaguchi N, Arai Y, Ozawa N, Hamada K, Nagao
N (2021) Investigation of
partially myristoylated carboxymethyl chitosan, anamphoteric-amphiphilic
chitosan derivative, as a new material for cosmetic and dermal application. J. Cosmet. Dermatol. 20, 2332–2340
Nakanishi T, Tanaka R, Tonai S, Lee JY, Yamaoka M, Kawai T, Okamoto A, Shimada M, Yamashita Y (2021) LH induces de novo cholesterol biosynthesis via SREBP activation in granulosa
cells during ovulation in female mice. Endocrinology. 162, bqab166 解説
八木俊樹, 藤田洋介, 上村慎治, 岩本裕之 (2021) 温度変化によって生じる鞭毛軸糸の構造変化 Spring8/SACLA 利用成果集(6号)9巻375-379
八木俊樹, 西山雅祥 (2021) 高圧力下で蘇る鞭毛運動『化学』(化学同人)(4号)76巻41-45
八木俊樹,
戸田暁之, 市川宗厳, 栗栖源嗣
(2021) 繊毛ダイニン軽鎖と重鎖微小管結合部位の複合体構造ー見えてきた軽鎖LC1の役割ー生物物理学会誌(1号)61巻20-22
伊原伸治, 佐々木ひかる, 中寺紗希 (2021)
モデル生物を用いた分泌タンパク質の凝集?脱凝集機構の解析. 月刊細胞 53: 63-65 解説
Nakanishi T, Okamoto A, Ikeda M, Tate S, Sumita M, Kawamoto R, Tonai S,
Lee JY, Shimada M, and Yamashita Y (2021) Cortisol induces
follicle regression, while FSH prevents cortisol-induced follicle regression in
pigs. Molecular Human Reproduction, gaab038 解説
Ihara S(2021)N-terminally
endogenous Mkate2-tagged Him-4 in Caenorhabditis elegans. Micropublication
Biology. 10.17912/micropub.biology.000386. 解説
Saitoh Y, Tanaka A, Hyodo S (2021) Protective
effects of polyvinylpyrrolidone-wrapped
fullerene against nitric oxide/peroxynitrite-induced cellular injury in human
skin keratinocytes. Journal of Nanoscience and Nanotechnology 21: 4579–4585 解説
Saitoh Y, Kawasaki N, Eguchi N, Ikeshima M (2021) Combined treatment
with dissolved hydrogen molecule and platinum nanocolloid exerts
carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation
and cell death in the human gastric cancer cell line NUGC-4. Free Radical Research 55: 211-220 解説
Fukunaga K, Matsuyama S, Abe A, Kobayashi M, Ito K(2021)Insertion of a transposable element in Less
Shattering1 (SvLes1) gene is not always involved in foxtail millet
domestication. ?Genetic Resources and Crop Evolution 68:
2923–2930 解説
2020年
福永健二, 大迫敬義 (2020) モデル植物となったエノコログサ―その雑草生物学への適用. 雑草研究65:140-149 解説
Tonai S, Kawabata A, Nakanishi T, Lee JY, Okamoto A, Shimada M, Yamashita Y (2020) Iron deficiency
induces female infertile in order to failure of follicular development in mice. Journal of Reproduction and Development 66:
475-483 解説
Abe Y, Asano T, Wakasa I, Kume A, Yokozawa S, Umemiya‐Shirafuji R, Suzuki H
(2020) Cryopreservation of canine spermatozoa using a
skim milk‐based extender and a short equilibration time. Reproduction in Domestic Animals 55: 1548–1553
Fukunaga K, Nur MZ, Inoue T, Taketa S, Ichitani K (2020) Phylogenetic analysis of the Si7PPO gene in foxtail millet, Setaria italica, provides further evidence for multiple
origins of the negative phenol color reaction phenotype. Genes and Genetic Systems 95: 191-199 解説
Saitoh Y, Umezaki T, Yonekura N, Nakawa A (2020) Resveratrol
potentiates intracellular ascorbic acid enrichment
through dehydroascorbic acid transport and/or its intracellular reduction in
HaCaT cells. Molecular Cellular Biochemistry
467:57-64 解説
Yagi T, Nishiyama M (2020) High hydrostatic
pressure induces vigorous flagellar beating in Chlamydomonas non-motile mutants
lacking the central apparatus. Scientific Reports 10: 2072 解説
プレスリリース
福永健二(2020) アワの栽培と加工(総説)生命環境学術誌 12:1-18
<書籍等>
菅裕(2023)ゲノムでたどる古代の日本列島(共著)東京書籍 解説
菅裕 (2023) 原生生物学事典(共著)朝倉書店 解説
〒727-0023
広島県庄原市七塚町5562
TEL 0824-74-1000
FAX 0824-74-0191