2) Li Q, Tanaka Y, Saitoh Y, Miwa N. Effects of Platinum Nanocolloid in Combination with Gamma Irradiation on Normal Human Esophageal Epithelial Cells. J Nanosci Nanotechnol.2016 16:5345-5352.
3) Saitoh
Y*,
Ikeshima M, Kawasaki N, MasumotoA, Miwa N. Transient generation of hydrogen
peroxide is responsible for carcinostatic effects of hydrogen combined with
platinum nanocolloid, together with increases intracellular ROS, DNA cleavages,
and proportion of G2/M-phase. Free Radical Res. 2016
Apr;50(4):385-95. doi: 10.3109/10715762.2015.1131823.
*Corresponding author
2015年
1)
Saitoh Y*,
Yoshimoto T, Kato S, Miwa N. Combined
treatment with ascorbic acid and a capacitive-resistive electric transfer
hyperthermic apparatus induces synergistically carcinostatic effects on Ehrlich
ascites tumor cell. Exp Oncol. 2015, 37(2):94-99. *Corresponding author
2) Li Q, Tanaka Y, Saitoh Y,
Tanaka H, Miwa N. Carcinostatic
effects of platinum nanocolloid combined with gamma irradiation on human
esophageal squamous cell carcinoma. Life Sci. 2015, 127:106-114. doi:
10.1016/j.lfs.2015.01.028.
3) Kato S, Kato Y, Shibata
H, Saitoh Y, Miwa N. Repressive
effects of oat extracts on intracellular lipid-droplet formation in adipocytes
and a three-dimensional subcutaneous adipose tissue model. Materials science and engineering
C. 2015, C49:269-273.
4) Ishikura H, Ono T, Oki S, Saito Y, Umei N,
Tsumiyama W, Tasaka A, Aihara K, Sato Y, Matsumoto T, Otsuka A. Effect of
stretch on improvement of muscular contractures in rats. J Phys Ther Sci. 2015, 27(9): 2821–2823. doi: 10.1589/jpts.27.2821
2014年
1) Kato S, Aoshima H, Saitoh Y, Miwa N.
Fullerene-C60 derivatives prevent UV-irradiation/TiO2-induced cytotoxicity on
keratinocytes and 3D-skin tissues through antioxidant actions. J
Nanosci Nanotechnol. 2014, 14(5):3285-3291.
2) Asada R, Liao F, Saitoh Y, Miwa N. Photodynamic anti-cancer
effects of fullerene [C60]-PEG complex on fibrosarcomas
preferentially over normal fibroblasts in terms of fullerene uptake and
cytotoxicity. Mol Cell Biochem. 2014, 390(1-2):175-184.
3) Haeiwa
H, Fujita T, Saitoh Y*, Miwa N. Oleic acid promotes adaptability against oxidative stress in 3T3-L1
cells through lipohormesis. Mol Cell Biochem.
2014, 386(1-2):73-83. DOI:
10.1007/s11010-013-1846-9. *Corresponding author
2013年
1) Saitoh Y, Morishita A, Mito S, Tsujiya T, Miwa N. Senescence-induced increases
in intracellular oxidative stress and enhancement of the need for ascorbic
acid in human fibroblasts. Mol Cell Biochem. 2013, 380(1-2):129-141. doi: 10.1007/s11010-013-1666-y.
2) Kato S,
Saitoh Y, Miwa N. Inhibitions
by hydrogen-occluding silica microcluster to melanogenesis in human pigment
cells and tyrosinase reaction. J Nanosci Nanotechnol. 2013,
13(1):52-59.
3) Kato S, Saitoh Y, Miwa N. Repressive
effects of a capacitive-resistive electric transfer (CRet) hyperthermic
apparatus combined with provitamin C on intracellular lipid-droplets formation
in adipocytes. Int J Hyperthermia.
2013, 29(1):30-37.
2012年
1) Saitoh Y, Mizuno H, Xiao L, Hyoudou S, Kokubo K, Miwa N. Polyhydroxylated
fullerene C60(OH) 44 suppresses intracellular lipid
accumulation together with repression of intracellular superoxide anion
radicals and subsequent PPARγ2 expression during spontaneous differentiation of
OP9 preadipocytes into adipocytes. Mol Cell Biochem. 2012, 366(1-2): 191-200.
2) Kato S,
Hokama R, Okayasu H, Saitoh Y, Iwai K, Miwa N. Colloidal platinum in hydrogen-rich water exhibits radical-scavenging
activity and improves blood fluidity. J. Nanosci.
Nanotechnol. 2012, 12(5): 4019-4027.
3) Asada R, Kageyama K, Tanaka H,
Kimura M, Saitoh Y, Miwa N. Carcinostatic effects of diverse ascorbate
derivatives in comparison with aliphatic chain moiety structures: Promotion by
combined hyperthermia and reduced cytotoxicity to normal cells. Oncol Lett. 2012,
3(5):1042-1046.
4) Kato S, Saitoh Y, Iwai K, Miwa N. Hydrogen-rich
electrolyzed warm water represses wrinkle formation against UVA ray together
with type-I collagen production and oxidative-stress diminishment in
fibroblasts and cell-injury prevention in keratinocytes. J
Photochem Photobiol B. 2012, 106(1):24-33.
5) Asada R, Kageyama K, Tanaka H, Saitoh Y, Miwa N. Anti-tumor and
anti-invasive effects of diverse musk-fragrant macrocyclic ketones and
their enhancement by hyperthermia. Mol Med Report 2012, 5(1):148-152.
2011年
1) Xiao L, Aoshima H, Saitoh Y, Miwa N. Highly hydroxylated fullerene localizes at the cytoskeleton and
inhibits oxidative stress in adipocytes and a subcutaneous adipose-tissue
equivalent. Free
Radic Biol Med. 2011, 51(7):1376-1389.
2) Kato S, Asada R, kageyama K, Saitoh Y,
Miwa N. Anticancer effects of 6-O-palmitoyl-ascorbate combined with a capacitive-resistive electric
transfer hyperthermic apparatus as compared with ascorbate in relation to
ascorbyl radical generation. Cytotechnology 2011, 63(4):425-435.
3) Kato S, Aoshima H, Saitoh Y, Miwa N. Fullerene-C60 incorporated in liposome
exerts persistent hydroxyl radical-scavenging activity and cytoprotection in
UVA/B-irradiated keratinocytes. J
Nanosci Nanotechnol. 2011,
11(5):3814-3823.
4) Liao F, Saitoh Y, Miwa N. Anticancer effects
of fullerene [C60] included in polyethylene glycol combined with visible light-irradiation through ROS generation and DNA fragmentation
on fibrosarcoma cells with scarce cytotoxicity to normal fibroblasts. Oncol Res. 2011,
19(5):203-216.
5) Kato S, Matsui H, Saitoh Y, Miwa N. Fish collagen-containing drink is
subcutaneously absorbed and attenuates the UVA-induced tissue-integrity
destruction and DNA damages in 3D-human skin tissue model. J
Funct Foods 2011, 3(1):50-55.
6) Saitoh Y,
Miyanishi A, Mizuno H, Kato S, Aoshima H,
Kokubo K, Miwa N. Super-highly hydroxylated fullerene derivative protects
human keratinocytes from UV-induced cell injuries together with the decreases
in intracellular ROS generation and DNA damages. J Photochem Photobiol B. 2011,
102(1):69-76.
1) Asada R, Kageyama K, Tanaka H, Matsui H, Kimura M, Saitoh
Y, Miwa N. Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell
death.
Oncol
Rep. 2010, 24(6):1463-1470.
2) Saitoh Y, Xiao L, Mizuno H, Kato S,
Aoshima H, Taira H, Kokubo K, Miwa N. Novel polyhydroxylated fullerene suppresses intracellular oxidative stress
together with repression of intracellular lipid accumulation during the
differentiation of OP9
preadipocytes into adipocytes. Free Radical Research 2010, 44(9):1072-1081.
3) Xiao L, Aoshima H, Saitoh Y, Miwa N. Fullerene-polyvinylpyrrolidone
clathrate localizes in the cytoplasm to prevent Ultraviolet-A ray-induced
DNA-fragmentation and activation of the transcriptional factor NF-kappa B. J Cell Biochem. 2010,
111(4):955-966.
4) Kato
S, Taira H, Aoshima H, Saitoh Y, Miwa N. Clinical Evaluation of Fullerene-C60
Dissolved in Squalane for Anti-Wrinkle Cosmetics. J Nanosci Nanotechnol. 2010,
10:6769-6774.
5) Kato S,
Aoshima H, Saitoh Y, Miwa N. Defensive effects
of fullerene-C60 dissolved in squalane against the 2, 4-nonadienal- induced
cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue
model. J Biomed Nanotechnol.
2010, 6:52-58.
6) Xiao L, Aoshima H, Saitoh
Y, Miwa N. The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied
oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system.
Biomaterials.
2010, 31:5976-5985.
7) Watanabe S, Saitoh
Y, Namba M, Miwa N. Administration with telomeric DNA telomere-like oligonucleotides induces
enhancement of telomerase activity and resistance against oxidative stress in
telomere reverse transcriptase gene-transfected human fibroblasts. Biomed Pharmacother. 2010, 64(8): 565-571.
8) SaitohY, Harata Y, Mizuhashi F, Nakajima
M, Miwa N. Biological safety of neutral-pH hydrogen-enriched electrolyzed water
upon mutagenicity, genotoxicity and subchronic oral toxicity. Toxicol
Ind Health 2010, 26(4):203-216.
9) Kato S, Kikuchi R, Aoshima
H, Saitoh Y, Miwa N. Defensive effects of fullerene-C60/liposome complex
against UVA-induced intracellular reactive oxygen species generation and cell
death in human skin keratinocytes HaCaT, associated with intracellular uptake
and extracellular excretion of fullerene-C60. J
Photochem Photobiol B. 2010,
98(2):144-151.
10) Kato S, Aoshima H, Saitoh Y, Miwa
N. Fullerene-C60/liposome complex: Defensive effects against UVA-induced
damages in skin structure, nucleus and collagen type I/IV fibrils, and the
permeability into human skin tissue. J
Photochem Photobiol B. 2010,
98(1):99-105.
1) Saitoh Y, Yumoto A, Miwa N.
2) Sugimoto M, SaitohY, Ichihashi M, Miwa N.
3)